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. 2024 May 27;9:128. doi: 10.1038/s41392-024-01828-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 9 — Notch signaling pathway in tumor suppression. Earlier studies provided evidence supporting Notch-mediated tumor suppression in various malignancies, including SCC, cervical cancer, and SCLC. (Figure created using BioRender.com). PDAC pancreatic ductal adenocarcinoma, MmuPV1 Mus musculus papillomavirus 1, HPV8 human papillomavirus, Co-A coactivator, MAML mastermind-like, CSL CBF1/suppressor of hairless/Lag1, hASH1 human achaete-scute homolog-1, SST somatostatin, SSTR somatostatin receptor, SCC squamous cell carcinoma, SCLC small cell lung cancer