Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 May 13;11:1400780. doi: 10.3389/fcvm.2024.1400780

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2024 Xin, Zhang, Lv, Xu, Liu, Li, Li, Han and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Common mechanisms of VSMC phenotypic transition. This diagram offers a detailed overview of the multifaceted mechanisms influencing the phenotypic transition of VSMCs. It delineates the interplay between pivotal signaling pathways: TGFβ, MAPK, Wnt, and Notch. The illustration details the modulatory impacts of miRNAs and LncRNAs, which can either inhibit or promote these transitions. Furthermore, it outlines the effects of ECM components and cytokines on this process. Collectively, the schematic underscores the complex network of interactions that modulate the functional dynamics and characteristics of VSMCs.