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. 2024 May 7;67(10):8122–8140. doi: 10.1021/acs.jmedchem.4c00220

Figure 4.

Figure 4

KINOMEscan, Eurofins DiscoverX, for compounds 25 (a) and 27 (b) at 1 μM concentration. Ten and 5 out of 403 kinases were inhibited with S(10) selectivity scores of 0.025 and 0.012, respectively.