Table 4.
Biochemistry analysis and complete blood count data in relation to survival to hospital discharge in 101 cats with histoplasmosis treated with antifungal therapy
| Variable | Survival status | Median (IQR) | <Lower reference limit | ⩽Half lower reference limit | >Upper reference limit | ⩾Twice upper reference limit |
|---|---|---|---|---|---|---|
| WBC count (103/μl) | Yes | 9.9 (8.8) | 12/89 (13%) | 3/89 (3%) | 15/89 (17%) | 2/89 (2%) |
| No | 5.9 (8.2) | 3/12 (25%) | 0/12 (0%) | 1/12 (8%) | 0/12 (0%) | |
| P = 0.383 | P = 1.0 | P = 0.687 | P = 1.0 | |||
| Segmented neutrophil count (103/μl) | Yes | 6.1 (7.2) | 9/89 (10%) | 3/89 (3%) | 23/89 (26%) | 2/89 (2%) |
| No | 4.6 (6.3) | 4/12 (33%) | 1/12 (8%) | 2/12 (17%) | 0/12 (0%) | |
| P = 0.048 | P = 0.405 | P = 0.725 | P = 1.0 | |||
| Band neutrophil count (/μl) | Yes | 0 (180) | NA | NA | 16/89 (18%) | 4/89 (4%) |
| No | 170 (280) | NA | NA | 3/12 (25%) | 2/12 (17%) | |
| P = 0.693 | P = 0.148 | |||||
| Lymphocyte count (103/μl) | Yes | 2.5 (2.5) | 15/89 (17%) | 3/89 (3%) | 2/89 (2%) | 0/89 (0%) |
| No | 0.9 (1.2) | 7/12 (58%) | 3/12 (25%) | 1/12 (4%) | 0/12 (0%) | |
| P = 0.004 | P = 0.022 | P = 0.322 | P = 1.0 | |||
| Eosinophil count (/μl) | Yes | 110 (320) | NA | NA | 3/88 (3%) | 1/88 (1%) |
| No | 70 (150) | NA | NA | 0/12 (0%) | 0/12 (0%) | |
| P = 1.0 | P = 1.0 | |||||
| Hematocrit (%) | Yes | 28 (14) | 46/89 (52%) | 4/89 (4%) | 1/89 (1%) | NA |
| No | 23 (18) | 8/12 (67%) | 2/12 (17%) | 0/12 (0%) | NA | |
| P = 0.373 | P = 0.149 | P = 1.0 | ||||
| Albumin (g/dl) | Yes | 2.7 (0.7) | 34/87 (39%) | 0/87 (0%) | NA | NA |
| No | 2.8 (0.8) | 3/12 (25%) | 1/12 (8%) | |||
| P = 0.526 | P = 0.121 | |||||
| Globulin (g/dl) | Yes | 4.3 (1.2) | NA | NA | 14/84 (17%) | NA |
| No | 4.4 (0.9) | 1/12 (8%) | ||||
| P = 0.684 | ||||||
| ALT (IU/l) | Yes | 37 (32) | 3/87 (3%) | NA | 4/87 (5%) | 2/87 (2%) |
| No | 50 (62) | 1/12 (8%) | 2/12 (17%) | 0/12 (0%) | ||
| P = 0.408 | P = 0.153 | P = 1.0 | ||||
| ALP (IU/l) | Yes | 26 (24) | 5/86 (6%) | NA | NA | NA |
| No | 30 (20) | 1/12 (8%) | ||||
| P = 0.553 | ||||||
| Creatinine (mg/dl) | Yes | 1.0 (0.4) | 12/88 (14%) | 0/88 (0%) | 4/84 (5%) | NA |
| No | 0.9 (0.6) | 3/12 (25%) | 1/12 (8%) | 0/12 (0%) | ||
| P = 0.382 | P = 0.120 | P = 1.0 | ||||
| BUN (mg/dl) | Yes | 19 (8) | 13/87 (15%) | NA | 5/87 (6%) | 2/87 (2%) |
| No | 22 (17) | 3/12 (25%) | 3/12 (25%) | 1/12 (8%) | ||
| P = 0.405 | P = 0.054 | P = 0.324 | ||||
| Cholesterol (mg/dl) | Yes | 128 (64) | 5/75 (7%) | NA | 0/75 (0%) | NA |
| No | 158 (106) | 0/12 (0%) | 2/12 (17%) | |||
| P = 1.0 | P = 0.018 | |||||
| Creatinine kinase (IU/l) | Yes | 185 (202) | 3/71 (4%) | NA | 3/71 (4%) | 0/75 (0%) |
| No | 375 (926) | 0/11 (0%) | 4/11 (36%) | 2/11 (18%) | ||
| P = 1.0 | P = 0.005 | P = 0.017 | ||||
| Bilirubin (mg/dl) | Yes | 0.2 (0.3) | NA | NA | 17/84 (20%) | 10/84 (12%) |
| No | 0.7 (1.5) | 8/12 (67%) | 4/12 (33%) | |||
| P = 0.002 | P = 0.071 | |||||
| Total calcium (mg/dl) | Yes | 9.2 (1.0%) | 7/83 (8%) | NA | 1/83 (1%) | NA |
| No | 9.3 (0.4%) | 0/12 (0%) | 0/12 (0%) | |||
| P = 0.590 | P = 1.0 |
Values in bold are P ⩽0.05
IQR = interquartile range; WBC = white blood cell; NA = not available; ALT = alanine transaminase; ALP = alkaline phosphatase; BUN = blood urea nitrogen