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. 2024 May 13;14:1367603. doi: 10.3389/fonc.2024.1367603

Table 4.

The rate of complication for rebiopsy in different factors (N = 113).

Variables Factors Complication status p-value
Complication (n = 37) Noncomplication (n = 76)
Age (year) 59.0 ± 9.6 59.2 ± 10.9 0.891
Sex Male 24 (64.9%) 30 (39.5%) 0.011
Female 13 (35.1%) 46 (60.5%)
Smoking status Yes 13 (35.1%) 18 (23.7%) 0.200
No 24 (64.9%) 58 (76.3%)
History of lung surgery Yes 5 (13.5%) 13 (17.1%) 0.624
No 32 (86.5%) 63 (82.9%)
ECOG performance status 0-2 35 (94.6%) 70 (92.1%) 0.926
3-4 2 (5.4%) 6 (7.9%)
Emphysema Yes 2 (5.4%) 5 (6.6%) 1.000
No 35(94.6%) 71(93.4%)
Treatment history TKI 10 (27.0%) 27 (35.5%) 0.048
Chemotherapy 11 (29.8%) 33 (43.4%)
TKI plus chemotherapy 16 (43.2%) 16 (21.1%)
Treatment time (M) ≤ 15 18(48.6%) 43(56.6%) 0.427
> 15 19(51.4%) 33(43.4%)
Target lesion Primary 21 (56.8%) 45 (59.2%) 0.804
Metastasis 16 (43.2%) 31 (40.8%)
Biopsy site Upper lobe 15 (40.5%) 43 (56.6%) 0.273
Middle lobe 3 (8.1%) 5 (6.6%)
Lower lobe 19 (51.4%) 28 (36.8%)
Tumor size (cm) ≤ 2 21 (56.8%) 3 0 (39.5%) 0.083
> 2 16 (43.2%) 46 (60.5%)
Biopsy method Single needle 12 (32.4%) 15 (19.7%) 0.138
Coaxial technique 25 (67.6%) 61 (80.3%)
Transfissural approach Yes 6 (16.2%) 2 (2.6%) 0.024
No 31 (83.8%) 74 (97.4%)
Pleura-to-target distance (cm) ≤ 3 21 (56.8%) 54 (71.1%) 0.131
> 3 16 (43.2%) 22 (28.9%)
Total biopsy time (min) ≤ 10 9 (24.3%) 28 (36.8%) 0.183
> 10 28 (75.7%) 48 (43.2%)