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. 2014 Jul 1;2014(7):CD004687. doi: 10.1002/14651858.CD004687.pub4

Piper 1990.

Methods RCT (participants matched in pairs by QOR, sex and age, then assigned to 1 condition or another) with cross‐over design. Wait‐list controls were used here for comparison
Participants 105 psychiatric outpatients referred from a walk‐in clinic. Axis I DSM‐III diagnoses were affective (31%), adjustment (23%), anxiety (7%) and impulse control (8%). 32% of participants had axis II diagnoses. Mean age 31 years, 65% female
Interventions Intervention: short‐term individual psychotherapy, manualised, based on Malan 1976 and Strupp 1984, for a maximum of 20 weekly 50‐min sessions (actual mean 18.6)
Control: wait‐list subsequently received STI therapy. Sessions were audio‐recorded, rated by Therapist Intervention Rating System. 8 therapists, mean experience 11.5 years (range 4‐35)
Outcomes QOR, SAS, Interpersonal Dependency Scale (2 subscales used), Interpersonal Behaviour Scale, GSI of SCL‐90, BDI, Trait Anxiety Scale, Rosenberg's Pre‐(therapy, wait‐list), post (therapy, wait), follow‐up/post‐therapy, then overall follow‐up ‐ 5‐month intervals. Self‐Esteem Scale, Insight Scale, life satisfaction by 7‐point Likert scale
Notes Only immediately post‐treatment data used for SCL‐90, BDI and Trait Anxiety Scale
 Unable to use SAS data as not presented with means and standard deviations
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "The research coordinator matched patients in pairs...and randomly assigned one member to the immediate therapy condition and the other member to the delayed therapy control condition"
Comment: insufficient information about the sequence generation process
Allocation concealment (selection bias) Unclear risk Comment: insufficient information provided
Blinding (performance bias and detection bias) 
 All outcomes Low risk Comment: self report data (SCL‐90, BDI, STAI) considered low risk of detection bias
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Comment: it was reported that 11 in the immediate therapy condition and 9 in the delayed therapy condition dropped out, and 67/86 provided follow‐up data. Insufficient information was provided on reasons for missing data to determine judgement of bias
Selective reporting (reporting bias) High risk Comment: ≥ 1 outcomes are reported incompletely so they could not be entered in a meta‐analysis
Other bias Unclear risk Comment: insufficient information to permit judgement