Table 2.
Characteristics of the patients with HCC on non-cirrhotic liver
| Variables | HCC on non-cirrhotic liver (n = 14) Median (Q1–Q3) or n (%) |
||||
|---|---|---|---|---|---|
| Number of lesions | 2 (1–3) | ||||
| Number of lesions > 3 | 2 (14.3) | ||||
| Diameter of major lesion (cm) | 9.5 (6.1–12.3) | ||||
| Sum of dimensions (cm) | 11.6 (8.5–14.2) | ||||
| Sum of dimensions > 5 cm | 12 (85.7) | ||||
| Sum of dimensions > 8 cm | 10 (71.4) | ||||
| Multifocality | 7 (50.0) | ||||
| Bilobar involvement | 5 (35.7) | ||||
| Macrovascular invasion | 6 (42.9) | ||||
| Microvascular invasion | 9 (64.3) | ||||
| Poor grading | 10 (71.4) | ||||
| Exceeding MC | 14 (100.0) | ||||
| Exceeding UCSF | 12 (85.7) | ||||
| Post-LT HCC recurrence | 8 (57.1) |
| % of steatosis | Metavir fibrosis score | HAI | |||
|---|---|---|---|---|---|
| Category | N (%) | Category | N (%) | Grade | N (%) |
| Absence | 4 (28.6) | Absence | 8 (57.1) | 0 | 4 (28.6) |
| 1: < 33% | 2 (14.3) | 1: Mild | 1 (7.1) | 1 | 1 (7.1) |
| 2: 33–66% | 4 (28.6) | 2: Moderate | 4 (28.6) | 2 | 2 (14.3) |
| 3: > 66% | 4 (28.6) | 3: Marked | 1 (7.1) | 3 | 2 (14.3) |
| 4: Cirrhosis | 0 (–) | 4 | 3 (21.4) | ||
| 5 | 2 (14.3) | ||||
Liver parenchyma was analyzed for grading of steatosis according to Brunt et al., for fibrotic state according to Metavir score, and for inflammatory activity according to HAI proposed by Knodell and Ishak
HCC hepatocellular carcinoma, Q1–Q3 first-third quartile, n number, MC Milan Criteria, UCSF University of California San Francisco, LT liver transplantation, HAI Histological Activity Index