Table 1.
Clinicopathological features of the CUP patients
| Variable | n (%) |
|---|---|
| CUPs patients | 166 |
| Age (years) | |
| Mean [SD] | 60.4 [12.4] |
| Min–max | 20–89 |
| Gender | |
| Male | 83 (50.0) |
| Female | 83 (50.0) |
| Smoking | |
| Current or former smoker | 73 (44.0) |
| Non-smoker | 77 (46.4) |
| Unknown | 9.6 (16.0) |
| Alcohol consume | |
| Current or former alcohol drinker | 40 (24.1) |
| Non-alcohol drinker | 104 (62.7) |
| Unknown | 22 (13.3) |
| Cancer family history | |
| Yes | 64 (38.6) |
| No | 72 (43.4) |
| Unknown | 30 (18.1) |
| Histology | |
| Adenocarcinoma | 104 (62.6) |
| Carcinoma | 43 (26.0) |
| Squamous cell carcinoma | 19 (11.4) |
| Metastasis site | |
| Lymph node | 99 (59.6) |
| Liver | 83 (50.0) |
| Lung | 54 (32.5) |
| Bone | 68 (41.0) |
| CNS | 9 (5.4) |
| Other | 34 (20.5) |
| Biopsy site (tissue analyzed) | |
| Liver | 35 (32.1) |
| Lymph node | 32 (29.4) |
| Bone | 26 (23.9) |
| CNS | 4 (3.7) |
| Other | 12 (11.0) |
| Dominant site of metastasis | |
| Visceral | 76 (45.8) |
| Lymph node | 41 (24.7) |
| Bone | 31 (18.7) |
| CNS | 5 (3.0) |
| Other | 13 (7.8) |
| Performance Status ECOG | |
| < 2 | 63 (38.0) |
| ≥ 2 | 56 (33.7) |
| Unknown | 47 (28.3) |
| Treatment cathegory | |
| Surgery any time | 21 (12.7) |
| Radiation therapy any time | 52 (31.3) |
| 1st Line chemotherapy | 80 (48.2) |
| 2nd Line chemotherapy | 28 (16.9) |
| > 2 Lines of chemotherapy | 11 (6.6) |
| 1st Line type of chemothterapy | |
| Carboplatin/Paclitaxel | 42 (25.3) |
| Cisplatin/Gemcitabine | 9 (5.4) |
| Other | 29 (17.5) |
| Not applicable | 86 (51.8) |
SD: Standard deviation; CNS: Central Nervous System