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. 2024 May 27;14:12132. doi: 10.1038/s41598-024-63045-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Evaluation results of PD mouse model (A) Number of APO-induced rota-tions in mice within 30 min; (B,C) Immunohistochemical staining of TH in the striatum and SNpc of each mouse group; (D) TH protein expression in the right striatum (n = 5); (E) Comparison of TH-positive nerve fibers expression in the right/left striatum between mouse groups (n = 6); (F) Comparison of TH-positive cells in the right/left SNpc (n = 4). For statistical significance comparisons, the following symbols were used: ^##C vs PD, P < 0.01; ^###C vs PD, P < 0.001; *PD vs PE, P < 0.05; ^&&CE vs PE, P < 0.01.