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. 2024 May 27;14:12132. doi: 10.1038/s41598-024-63045-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of optogenetic stimulation on motor behavior of mice and evaluation results of mouse optogenetic model. (A) expression of dorsal striatal AAV protein on the right and left side; (B) Changes in left forelimb usage rate before and after light stimulation, the left figure shows the intra group comparison of each group before and after light stimulation, left figure shows the comparison results between groups; (C) Changes in the time of pole test before and after light stimulation (n = 6).