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. 2024 May 27;14:12101. doi: 10.1038/s41598-024-63101-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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OB and mPFC theta power during anxiety. (A–D) Theta PSD (left panels) and average power (right panels) of OB (A, B) and mPFC (C, D) in the EPM (n = 26) (A, C) and OF (n = 24) (B, D) experiments (baseline: n = 15, n = 39, respectively). Data presented as mean ± SEM in the PSDs. Bars represent median values in the bar plots. Statistical difference measured by Mann–Whitney test. *p < 0.05, **p < 0.01, ***p < 0.001. PSD, power spectral density; OB, olfactory bulb; mPFC, medial prefrontal cortex; EPM, elevated plus maze; OF, open field.