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. 2024 May 14;15:1396793. doi: 10.3389/fendo.2024.1396793

Table 2.

Descriptive statistics based on the smoking status.

Primary infertile men(N=1430) Secondary infertile men(N=508)
non-smokers
(n=817)
Moderate smokers(n=405) Heavy smokers(n=208) P non-smokers(n=250) Moderate smokers(n=163) Heavy smokers(n=95) P
Age(year),mean ± s.d. 29.8 ± 3.9 29.2 ± 4.0 30.1 ± 4.8 0.04 32.4 ± 5.3 31.5 ± 5.3 33.7 ± 5.2 0.001
<40,n(%) 97.4(795) 98.3(398) 96.1(200) 0.28 89.6(224) 92.0(150) 84.2(80) 0.14
≥40,n(%) 1.5(21) 1.7(7) 3.8(8) 10.4(26) 8.0(13) 15.8(15)
BMI(kg/m^2),mean ± s.d. 24.8 ± 3.7 25.3 ± 4.4 25.1 ± 4.4 0.24 24.6 ± 3.5 25.0 ± 4.4 25.7 ± 5.0 0.39
<24,n(%) 43.0(351) 49.4(165) 42.8(89) 0.74 42.8(107) 44.8(73) 36.8(35) 0.45
≥24,n(%) 57.0(465) 50.6(240) 57.2(119) 57.2(143) 55.2(90) 63.2(60)
Duration of infertility,n(%) 0.11 0.18
≤1 year 76.2(622) 76.8(311) 71.6(149) 72.4(181) 72.4(118) 72.6(69)
>1 year,<3 year 14.4(118) 11.9(48) 13.0(27) 13.2(33) 16.0(26) 7.4(7)
≥3 year 9.4(77) 11.3(46) 15.4(32) 14.4(36) 11.6(19) 20.0(19)
Frequency of night snack intake,n(%) 0.0001 <0.0001
0/week 33.5(274) 25.2(102) 21.2(44) 50.0(125) 28.2(46) 24.2(23)
1-3/week 63.8(521) 70.4(285) 72.1(150) 47.6(119) 68.7(112) 70.5(67)
>3/week 2.7(22) 4.4(18) 6.7(14) 2.4(6) 3.1(5) 5.3(5)
Dietary habits,n(%) <0.0001 <0.0001
Regular diet(three meals per day) 72.3(591) 59.5(241) 47.1(98) 80.4(201) 60.7(99) 46.3(44)
Irregular diet 27.7(226) 40.5(164) 52.9(110) 19.6(49) 39.3(64) 53.7(51)
Work time, n(%) 0.06 0.89
<8(h/d) 32.3(264) 34.3(139) 34.6(72) 38.0(95) 38.0(62) 36.8(35)
8-10(h/d) 52.3(427) 46.1(187) 43.8(91) 44.0(110) 40.5(66) 45.3(43)
>10(h/d) 15.4(126) 19.5(79) 21.6(45) 18.0(45) 21.5(35) 17.9(17)
Sleep time, n(%) 0.36 0.06
≤8(h/d) 76.0(621) 72.3(293) 73.6(153) 75.6(189) 65.0(106) 69.5(66)
>8(h/d) 24.0(196) 27.7(112) 26.4(55) 24.4(61) 35.0(57) 30.5(29)
Semen parameters
Semen volume(ml),median(Q1,Q3) 3.3(2.3,4.4) 3.0(2.2,4.1) 2.8(2.0,4.0) 0.01 3.2(2.2,4.5) 3.0(2.1,4.1) 2.8(1.8,3.7) 0.008
Semen volume<1.5(ml),n(%) 7.6(62) 8.6(35) 12.0(25) 0.67 6.8(17) 9.2(15) 12.6(12) 0.22
Sperm concentration(×10^6/ml),
median(Q1,Q3)
68.6(36.0,121.7) 60.7(31.4, 101.8) 59.2(28.8,116.2) 0.01 77.9(45.6,129.4) 69.2(34.2, 120.8) 72.3(43.2,127.8) 0.18
Sperm concentration<15×10^6/ml,
n(%)
7.7(63) 12.1(49) 13.9(29) 0.005 5.6(14) 8.6(14) 10.5(10) 0.24
Progressive motility(%),median
(Q1,Q3)
41.5(28.8,52.8) 43.4(28.5,55.0) 45.5(28.9,55.7) 0.25 48.1(36.3,58.5) 46.4(34.2,60.1) 44.7(29.3,56.3) 0.01
Normal morphology(%),median
(Q1,Q3)
7(4,8) 6(5,8) 7(5,8) 0.7 6(5,8) 6(5,8) 6(4,8) 0.84
Normal morphology<4%,n(%) 23.7(193) 23.7(96) 19.7(41) 0.46 23.2(58) 16.6(27) 27.4(26) 0.10

P values are derived, unless otherwise noted, using analysis of variance.