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. 2024 May 14;15:1396793. doi: 10.3389/fendo.2024.1396793

Table 3.

Probability ratios with 95% confidence intervals for aberrant semen scope at varying degrees of tobacco use.

Primary infertile men Secondary infertile men
non-smokers
(n=817)
Moderate smokers(n=405) Heavy smokers(n=208) non-smokers
(n=250)
Moderate smokers(n=163) Heavy smokers(n=95)
Semen volume
Crude ref 1.15(0.74,1.76) 1.66(1.00,2.69) ref 1.39(0.67, 2.87) 1.98(0.89, 4.30)
P 0.52 0.04 0.37 0.09
Adjusted ref 1.13(0.71,1.76) 1.53(0.90,2.54) ref 1.16(0.53, 2.52) 1.18(0.48, 2.77)
P 0.61 0.11 0.71 0.71
Sperm concentration
Crude ref 1.65(1.11,2.44) 1.94(1.20,3.07) ref 1.58(0.73, 3.44) 1.98(0.83,4.60)
P 0.01 0.005 0.24 0.11
Adjusted ref 1.60(1.05, 2.40) 1.88(1.14,3.05) ref 1.38(0.61, 3.11) 1.65(0.65,4.06)
P 0.03 0.01 0.43 0.28
Total count
Crude ref 1.39(0.94, 2.04) 1.74(1.09,2.73) ref 1.48(0.71,3.10) 1.92(0.836,4.26)
P 0.09 0.02 0.29 0.11
Adjusted ref 1.39(0.92, 2.07) 1.76(1.08,2.81) ref 1.27(0.58,2.75) 1.67(0.68,3.93)
P 0.11 0.02 0.55 0.25
Progressive motility
Crude ref 0.98(0.75, 1.27) 0.91(0.65,1.276) ref 0.51(0.31,0.83) 0.54(0.29,0.96)
P 0.86 0.58 0.007 0.04
Adjusted ref 1.10(0.845,1.44) 1.00(0.70,1.42) ref 0.53(0.31,0.87) 0.53(0.28,0.99)
P 0.5 0.99 0.01 0.05
Total motility
Crude ref 0.88(0.69,1.13) 0.88(0.64,1.21) ref 0.61(0.39,0.96) 0.79(0.46,1.3)
P 0.32 0.45 0.03 0.37
Adjusted ref 0.95(0.73,1.23) 0.93(0.66,1.30) ref 0.63(0.39,1.01) 0.79(0.44,1.37)
P 0.7 0.67 0.06 0.40
Nomal morphology
Crude ref 0.88(0.58,1.32) 1.26(0.77,2.01) ref 0.41(0.15,0.98) 0.94(0.38,2.12)
P 0.55 0.34 0.06 0.89
Adjusted ref 0.96(0.62,1.46) 1.46(0.87,2.38) ref 0.37(0.13,0.93) 0.88(0.33,2.16)
P 0.86 0.14 0.05 0.79

Men having the following WHO-recognized semen quality values were used as the reference group for parameter analysis: semen volume ≥ 1.5 ml, sperm concentration ≥ 15 × 106/ml, and progressive motility sperm ≥ 32 × 106/ml. Crude: unmodified model Forage, BMI, period of abstinence, alcohol intake, length of infertility, how many nocturnal snacks consumed, dietary practices, and working hours were all changed in the model; ref stands for the reference.