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Left: Acetylcholine (Ach), Right: Sodium nitroprusside (SNP); ***P<0.001, sham vs all groups, **P<0.01, sham vs IR, IR+miR-486-5p, +P<0.05, sham vs IR+ scramble miRNA (scb); n = 9–14 rats per group for sham and IR groups and n = 6 rats per group for IR+miR-486-5p and IR+scb groups.
