TABLE 1.
Selected parameters from simulation study using sequential multiple assignment randomized trial (SMART), observational study (OS), and test datasets.
| SMART | OS | Test Dataset | |
|---|---|---|---|
| Number of participants | 630 | 1000 | 20,000 |
| Age (mean, sd) | 52 (8) | 52 (8) | 52 (8) |
| Opioid usage (Baseline) % | 0.2 | 0.2 | 0.2 |
| Depression symptoms (Baseline) % | 0.3 | 0.3 | 0.3 |
| Opioid usage (3 months) % |
p
= expit − 0.5
|
p
=1) = expit − 
|
p
= expit − 
|
| Depression symptoms (3 months) % |
p
= expit + 
|
p
= expit + 
|
expit + 
|
| Randomization probabilities at each stage |
p
= 0.5 |
p
= expit(−0.5 −  + 
|
p
= 0.5 |