Table 1.
Organ-restricted conditions in which the effect of eosinophilia remains unclear. Modified table taken from P. Valent et al., 2012 (ICOG-EO 2011)
| In these conditions the role of eosinophils has not been fully elucidated. The diagnosis of hypereosinophilic syndrome cannot be made when one of these entities is the only clinical manifestation of hypereosinophilia. | |
|---|---|
| Single-organ pathologies (nondermatologic) | Dermatologic diseases |
| Eosinophilic gastrointestinal disorders (eosinophilic esophagitis, gastroenteritis, or colitis) | Allergic contact dermatitis |
| Eosinophilic pancreatitis | Angiolymphoid hyperplasia with eosinophilia |
| Eosinophilic hepatitis | Annular erythema of infancy |
| Eosinophilic ascites | Atopic dermatitis |
| Pulmonary eosinophilic syndromes (eosinophilic asthma, bronchitis, pneumonia, or pleuritis) | Bullous pemphigoid |
| Eosinophilic nephritis | Coccidioidomycosis |
| Eosinophilic cystitis | Drug eruptions |
| Eosinophilic endometritis and myometritis | Eosinophilic fasciitis |
| Eosinophilic mastitis | Eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy |
| Eosinophilic ocular disorders | Eosinophilic pustular folliculitis: all variants |
| Eosinophilic myocarditis | Erythema toxicum neonatorum |
| Eosinophilic panniculitis | Eosinophilic ulcer of the oral mucosa |
| Eosinophilic synovitis | Eosinophilic vasculitis |
| Eosinophilic fasciitis | Granuloma faciale |
| Infestations (parasites/ectoparasites, including scabies, bed bugs, and cutaneous larva migrans) | |
| Incontinentia pigmenti | |
| Kimura disease | |
| Langerhans cell histiocytosis | |
| Mycosis fungoides and Sezary syndrome | |
| Pachydermatous eosinophilic dermatitis | |
| Pemphigoid variants, including bullous pemphigoid and pemphigoid gestationis | |
| Pemphigus variants | |
| Pregnancy-related dermatoses | |
| Pseudolymphoma | |
| Urticaria/angioedema | |
| Vasculitis | |
| Wells syndrome (eosinophilic cellulitis) | |