Table 1.
Baseline Patient Characteristics.
| Characteristics | Median (IQR) or N (%) |
|---|---|
| Age | 53.5 (46.5–59.5) |
| Race | |
| White | 53 (27.3) |
| Black/AA | 76 (39.2) |
| Latina | 28 (14.4) |
| Multiracial | 21 (10.8) |
| Other | 16 (8.2) |
| Post-menopausala | 124 (64.2) |
| Body Mass Index (BMI) (kg/m2) | 86 (78.5–93.5) |
| Average systolic blood pressure (mmHg) | 130 (116–142) |
| Average diastolic blood pressure (mmHg) | 86 (78.5–93.5) |
| Hypertension (≥130/80 mmHg) | 159 (82.0) |
| LDL cholesterol (mg/dL) | 93 (76.5–118) |
| HDL cholesterol (mg/dL) | 60 (47–73) |
| Diabetesb | 24 (12.4) |
| Prior MIb | 18 (9.3) |
| Prior strokeb | 24 (12.4) |
| Hep Cb | 61 (31.4) |
| HIVc | 62 (32) |
| Cocained,e | 109 (56.2) |
| Cocaethylened | 35 (18.0) |
| Levamisoled | 73 (37.6) |
| Methamphetamined | 56 (28.9) |
| Heroind,f | 4 (2.1) |
| Fentanyld | 3 (1.5) |
| Opioid analgesicsd,g | 45 (23.2) |
| Alcohold,h | 56 (28.9) |
| Cannabisd,i | 97 (50) |
| Nicotined | 134 (69.1) |
| Cotinined | 132 (68) |
| Promethazinej | 4 (2.1) |
| Methadonej | 40 (20.6) |
| Buprenorphinej | 0 (0) |
| Naloxonej | 0 (0) |
| Benzodiazapinesj,k | 17 (8.8) |
| Beta blockersj,l | 12 (6.2) |
| Calcium channel blockersj,m | 8 (4.1) |
| Other antihypertensive agentsj,n | 7 (3.6) |
| Statinsj,o | 0 (0) |
| Isosorbide Mononitratej | 0 (0) |
| Acetaminophenj | 51 (26.3) |
| Lidocainej | 32 (16.5) |
| Tenofovirj | 9 (4.6) |
| Emtricitabinej | 21 (10.8) |
| Darunavirj | 6 (3.1) |
| Raltegravirj | 1 (0.5) |
| Dolutegravirj | 26 (13.4) |
| LVMI (g/m2) | 86.8 (72.9–100) |
>1 year since last menstrual period;
Self reported history;
Immunoassay positive result;
Toxicology confirmed;
Cocaine, Benzoylecgonine, Ecgonine methyl ester or Norcocaine;
6-Monoacetylmorphine, Heroin;
Morphine, Codeine, Hydrocodone, Hydromorphone, Dihydrocodeine, Morphine Glucuronide, Codeine Glucuronide, Oxycodone or Oxymorphone;
Determined by Ethyl Glucuronide;
Tetrahydrocannabinol (THC) −COOH and THC−COOH glucuronide;
Drug level confirmed;
7-Aminoclonazepam, Clonazepam, Diazepam, Lorazepam, Nordiazepam, Temazepam, Oxazepam, Alprazolam, alpha-hycroxyalprazolam, Flurazepam, 2-Hydroxyethlflurazepam, Desalkylflurazepam, Flunitrazepam, 7-aminoflunitrazepam, N-Desmethylflunitrazepam, Midazolam, 7-aminontrazepam or Etizolam;
Metoprolol, Atenolol, Carvedilol, Labetolol;
Amlodipine, Diltiazem, Verapamil;
Clonidine, Lisinopril or Losartan;
Atorvastatin, Pravastatin or Simvastatin.