Table 1. Summary of case reports on Fosmanogepix.
Author (s) | Case summary | Duration of Therapy | Outcome |
Camargo et al. [40] | A 40-year-old male who underwent HSCT for Hodgkin's lymphoma (HL) experienced complications with graft-versus-host disease (GvHD) and subsequently developed a disseminated infection with multi-drug-resistant Aspergillus calidoustus | It is approximately 191 days, though it is not explicitly mentioned | Significant improvement with negative serum galactomannan |
Winston et al. [45] | A 26-year-old with AML faced a Fusarium lactis infection, resistant to azoles and echinocandins. FMGX combined with liposomal AMB | 6 months | Clinical improvement, reductions in brain lesions, and an absolute neutrophil count rise, resulting in AML remission |
Goggin et al. [46] | A 14-year-old with immunodeficiency and end-stage kidney disease has had persistent cutaneous Fusariosis since age 3. Despite prior unsuccessful treatments, FMGX was successful, leading to negative skin biopsies | 6 months | Clinical improvement with negative skin biopsies |