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. Author manuscript; available in PMC: 2024 May 28.
Published in final edited form as: Trends Parasitol. 2018 Jun 29;34(8):683–693. doi: 10.1016/j.pt.2018.05.006

Table 2:

Tv immune-evasive behaviors

Behavior Function or Effector Predicted Outcome Reference
Immune cell lysis Kill T-cells Dampen adaptive immunity [25]
Kill B-cells Dampen humoral immunity [25]
DNase II Production Degrade NETs (putative) Evade neutrophil NETosis [74]
Cysteine Protease production Degrade antibody Evade neutrophil trogocytosis [75], [70]
Clumping Tetraspanin 8, palmitoylated proteins, others unknown Evade Neutrophil trogocytosis Enhance adherence to host cells [22], [23], [31], [70] [22], [23], [21]
Exosome Secretion Increase IL-10, decrease IL-8 and IL-17 Promote immunological tolerance [32], [78], [59]