Table 2:
Behavior | Function or Effector | Predicted Outcome | Reference |
---|---|---|---|
Immune cell lysis | Kill T-cells | Dampen adaptive immunity | [25] |
Kill B-cells | Dampen humoral immunity | [25] | |
DNase II Production | Degrade NETs (putative) | Evade neutrophil NETosis | [74] |
Cysteine Protease production | Degrade antibody | Evade neutrophil trogocytosis | [75], [70] |
Clumping | Tetraspanin 8, palmitoylated proteins, others unknown | Evade Neutrophil trogocytosis Enhance adherence to host cells | [22], [23], [31], [70] [22], [23], [21] |
Exosome Secretion | Increase IL-10, decrease IL-8 and IL-17 | Promote immunological tolerance | [32], [78], [59] |