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. Author manuscript; available in PMC: 2024 May 28.
Published in final edited form as: Biomaterials. 2023 Mar 7;296:122076. doi: 10.1016/j.biomaterials.2023.122076

Table 1.

IC50 to doxorubicin.

Scaffold OS OS OS/TAM OS/TAM
DOX DOX + 5.1 μM Stattic DOX DOX + 5.1 μM Stattic
PCL 0.086 (0.041 – 0.133) 0.802 (0.394 – 2.595) 0.059 (0.032 – 0.089) 0.037
20% Gelatin 0.011 (1.69 × 10−5 – 0.031) 0.037 (0.014 – 0.065) 0.072 (0.037 – 0.114) 0.146 (0.008 – 0.444)
50% Gelatin 0.117 (0.093 – 0.145) 0.193 (0.115 – 0.308) 0.100 (0.067 – 0.148) 0.125 (0.087 – 0.172)
80% Gelatin 0.149 (0.118 – 0.187) 0.176 (0.102 – 0.284) 0.179 (0.127 – 0.250) 0.285 (0.140 – 0.522)
100% Gelatin 0.113 (0.078 – 0.159) 0.093 (0.053 – 0.142) 0.035 (0.010 – 0.060) 0.336 (0.136 – 0.821)

IC50 is given in μM of doxorubicin (DOX) with the 95% confidence interval shown in parentheses.