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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Neuroimage. 2024 Apr 20;293:120622. doi: 10.1016/j.neuroimage.2024.120622

Table 1.

Test statistics evaluated in the present study.

Test statistic Description
Mean The mean value of the correlations within the gene set
Meanabs The mean value of the absolute correlations within the gene set
Meansqr The mean value of the squared correlations within the gene set
Maxmean Either the mean value of positive correlations or the mean value of negative correlations within the gene set, depending on which is greater.
Median The median value of the correlations within the gene set
Sig Number The number of significant (FDR-corrected) correlations within the gene sets.
Kolmogorov-Smirnov (KS) Compute the cumulative sum for the ranked correlations between all genes and brain profiles. For each gene, increment the cumulative sum if it belongs to the gene set and decrement it otherwise. Each gene has equal weight in either the increment or the decrement, with a value of 1. The KS is calculated as the maximum deviation from zero of the cumulative sums.
Weighted KS Same as above except that the increment or decrement is weighted by the correlation strength of the gene.