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. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: Clin Trials. 2024 Apr 9;21(3):322–330. doi: 10.1177/17407745231221152

Figure 1.

Figure 1.

Trial data from an illustrative simulated example using a TITE-CRM with a 16-week observation window for toxicity (plot on top) and 4-week observation window (plot on bottom), a total sample size of 30 patients, an accrual rate of 2 patients per month. DL: dose level, DLT: Dose-limiting toxicity