Table 6.
Relationship between VGAM volume and outcomes and embolization complications
| V3D SLICER | ||||
|---|---|---|---|---|
| n (%) | Med (IQR) | p-value | ||
| Short-term outcomes | ||||
| Heart failure (n = 39)* | 20 (51) | 5.19 (3.81–10.69) | 0.120 | |
| NAR (n = 36)§ | 17 (44) | 5.17 (3.79–9.30) | 0.208 | |
| Deaths (n = 43) | 7 (16) | 5.17 (3.81–10.49) | 0.323 | |
| I/H lesions at first MRI (n = 43) | 13 (30) | 4.70 (3.60–10.70) | 0.425 | |
| WM signal alterations (n = 43) | 18 (42) | 4.88 (3.34–10.59) | 0.176 | |
| Global brain atrophy (n = 43) | 3 (7) | 10.49 (2.66–17.84) | 0.321 | |
| Long-term outcomes | ||||
| POPC score (n = 36)^ | 1 | 26 (60) | 4.71 (2.57–7.32) | 0.337 |
| 2 | 3 (7) | 3.94 (3.76–4.43) | ||
| 3 | 2 (5) | 12.40 (n.a.) | ||
| 4 | 5 (12) | 3.44 (2.38–12.01) | ||
| Epilepsy (n = 36)^ | 8 (22) | 5.36 (2.87–12.15) | 0.421 | |
| Treatment | ||||
| Embolization complications (n = 35) | 17 (48.5) | 5.05 (3.81–10.49) | 0.657 | |
EVT endovascular treatment, I/H ischemic/hemorrhagic, IQR interquartile range, n.a. not applicable, NAR neonates at risk, Med median, MRI magnetic resonance imaging, POPC Pediatric Overall Performance Category, WM white matter
*Analysis performed in the 39 subjects presenting in the neonatal period
§Three neonates who died after palliation for severe brain lesions were excluded from the analysis
^Analysis performed in the 36 surviving subjects