Table 2.
Ovarian stimulation in the patients in each group.
Items | Group A | Group B | Group C | Group D | χ2/F | P value |
---|---|---|---|---|---|---|
No. of patients | 3038 | 3228 | 3436 | 3172 | ||
dosage of Gn (U) | 1875 (1425–2400) | 2100 (1650–2700) a | 2325 (1800–2850) ab | 2625 (2100–3150) abc | 1198.753 | 0.000 |
duration of Gn (d) | 10.0 ± 1.6 | 10.1 ± 1.6 | 10.2 ± 1.5a | 10.3 ± 1.7ab | 13.600 | 0.000 |
LH on hCG injection day (IU/L) | 1.4 (0.9–2.2) | 1.8 (1.1–2.8) a | 1.9 (1.1–3.1) ab | 2.1 (1.2–3.6) abc | 454.564 | 0.000 |
E2 on hCG injection day (pmol/L) | 6834 (5110–9382) | 6953 (5167–9963)a | 7164 (5270–10235) ab | 6498 (4574–9276) abc | 90.621 | 0.000 |
P on hCG injection day (nom/L) | 1.4 (1.1–1.7) | 2.1 (1.6–2.5) a | 2.6 (2.0–3.3) ab | 3.2 (2.4–4.9) abc | 5280.862 | 0.000 |
P/E2 ratio | 0.23 (0.17–0.31) | 0.33 (0.24–0.44) a | 0.40 (0.31–0.53) ab | 0.55 (0.42–0.74) abc | 4695.487 | 0.000 |
P/O ratio | 0.11 (0.09–0.13) | 0.18 (0.16–0.20) a | 0.26 (0.24–0.29) ab | 0.43 (0.37–0.54) abc | 12072.402 | 0.000 |
Endometrial thickness on hCG day(cm) | 10.8 ± 1.4 | 10.7 ± 1.4 | 10.6 ± 1.4ab | 10.6 ± 1.5ab | 18.199 | 0.000 |
No. of oocytes retrieved | 13 (11–16) | 12 (9–14) a | 10 (8–13) ab | 7 (5–9) abc | 3928.658 | 0.000 |
MII oocyte rate (%) | 76.3 | 76.6 | 79.4 ab | 81.0ab | 118.840 | 0.000* |
ICSI rate (%) | 43.9 | 41.3 | 41.5 | 38.4 abc | 19.611 | 0.000* |
Available embryo number | 4 (3–7) | 3 (2–5) a | 3 (2–5) ab | 2 (2–3) abc | 988.474 | 0.000 |
Ratio of available embryos to retrieved oocytes (%) | 35.9 | 35.8 | 36.7 | 40.9abc | 106.512 | 0.000 |
a indicates P<0.05 compared with Group A; b indicates P<0.05 compared with Group B; c indicates P<0.05 compared with Group C. * indicates a significant difference between the two groups (P<0.008).