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. 2024 May 15;5:1352711. doi: 10.3389/fpain.2024.1352711

Figure 6.

Figure 6

Quantitative sensory testing (QST) correlations. Scatter plots for the significant QST correlations (which withstood correction for multiple testing) within both patient groups combined (A) and FD patients (B). In the case of the PNP patients, the calculations did not withstand correction for multiple testing. (A) The correlation between CDT and the PDQ score indicates that a loss of cold fiber function is associated with a neuropathic pain (NP) component and the sensory symptom of pain attacks. (B) Cold fiber function loss is strongly correlated with NP in FD patients. The loss of C-fiber function was associated with higher ratings in the FabryScan and a stronger sensation of numbness. CDT, cold detection threshold; WDT, warm detection threshold; QST, quantitative sensory testing; FD, Fabry disease; PNP, polyneuropathy; PDQ, painDETECT questionnaire.