Table 1.
Demographic data.
| FD | PNP | Control | ||||
|---|---|---|---|---|---|---|
| n | mean ± SD | n | mean ± SD | n | mean ± SD | |
| Age (years) | 16 | 44.25 ± 17.92 (34.7; 53.8) | 21 | 64.62 ± 11.19 (59.53; 69.71) | 23 | 46.83 ± 19.53 (38.38; 55.27) |
| Height (cm) | 16 | 168.69 ± 8.36 (164.23; 173.14) | 21 | 178.57 ± 9.11 (174.43; 182.72) | 23 | 174.13 ± 8.78 (170.33; 177.93) |
| N2 hand (ms) | 13 | 369.00 ± 76.60 (322.71; 415.29) | 15 | 414.27 ± 76.23 (372.05; 456.48) | 23 | 388.00 ± 45.61 (368.28; 407.72) |
| P2 hand (ms) | 13 | 473.54 ± 77.21 (426.88; 520.2) | 15 | 519.73 ± 85.81 (472.21; 567.25) | 23 | 496.57 ± 52.65 (473.8; 519.33) |
| Amplitude hand (µV) | 13 | 11.69 ± 3.67 (9.47; 13.9) | 16 | 7.69 ± 4.5 (5.29; 10.09) | 23 | 10.07 ± 2.80 (8.86; 11.28) |
| Cold rating hand dorsum | 16 | 2.94 ± 1.95 (1.9; 3.98) | 21 | 2.07 ± 1.47 (1.4; 2.74) | 23 | 3.23 ± 1.37 (2.64; 3.82) |
| N2 foot (ms) | 13 | 487.54 ± 98.93 (427.76; 547.32) | 11 | 645.73 ± 174.75 (528.33; 763.13) | 22 | 501.36 ± 49.46 (479.43; 523.29) |
| P2 foot (ms) | 13 | 583.15 ± 95.30 (525.56; 640.74) | 11 | 741.18 ± 188.21 (614.74; 867.63) | 22 | 607.36 ± 50.68 (584.89; 629.83) |
| Amplitude foot (µV) | 14 | 8.02 ± 3.59 (5.95; 10.1) | 18 | 5.16 ± 5.82 (2.26; 8.05) | 22 | 8.29 ± 3.93 (6.54; 10.03) |
| Cold rating foot dorsum | 16 | 2.63 ± 2.27 (1.42; 3.84) | 21 | 1.36 ± 1.75 (0.57; 2.16) | 23 | 3.02 ± 1.54 (2.36; 3.69) |
| CDT foot Z value | 16 | −1.29 ± 1.37 (−2.01; −0.56) | 21 | −1.84 ± 1.43 (−2.49; −1–19) | 23 | 0.04 ± 0.99 (−3.89; 0.46) |
| PDQ score | 16 | 15.94 ± 8.505 (11.41; 20.47) | 21 | 13.71 ± 8.84 (9.69; 17.74) | n/a | n/a |
| FabryScan score | 14 | 16.14 ± 4.33 (13.64; 18.64) | n/a | n/a | n/a | n/a |
Cold-evoked potential (CEP) values and questionnaire scores for each subject group.
FD, Fabry disease; PNP, polyneuropathy; PDQ, painDETECT questionnaire; CDT, cold detection threshold. The lower and upper 95% confidence limits are presented in brackets below the mean ± standard deviation. Patients with clearly abolished potentials were given an amplitude of “0,” hence the partial discrepancy of the patient numbers for latencies and amplitudes.