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. 2024 May 15;14:1395978. doi: 10.3389/fonc.2024.1395978

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Copyright © 2024 Sussman, Severgnini, Giobbie-Hurder, Friedlander, Swanson, Jaklitsch, Clancy, Goguen, Lautz, Swanson, Daley, Ritz, Dranoff and Hodi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan-Meier plots of biomarkers related to improved PFS. (A) Patients with pre-treatment MMP-1 expression above the median of 20.9 was associated with significantly improved PFS (log-rang p=0.009); (B) Patients with TRAIL expression above the median of 2.86 was associated with significantly better PFS (p = 0.01). (C) Patients with CXCL-11 expression above median of 2.44 was associated with significantly better PFS (p=0.03); and (D) Patients with CXCL-13 expression above the median of 2.76 was associated with significantly better PFS (p = 0.05).