IC50 of compounds 13a, 13b, and 13d–13f.
Compound | IC50 (μM) | ||
---|---|---|---|
NO | IL-6 | TNF-α | |
DEX | 21.197 ± 0.517 | 0.247 ± 0.073 | 27.796 ± 0.643 |
13a | 61.494 ± 0.560 | 1.437 ± 0.351 | 62.835 ± 1.198 |
13b | 10.992 ± 0.328 | 2.294 ± 0.791 | 12.901 ± 1.591 |
13d | 19.969 ± 0.674 | 4.715 ± 1.995 | 22.044 ± 0.449 |
13e | 22.143 ± 1.019 | 4.879 ± 0.112 | 21.795 ± 1.143 |
13f | 36.041 ± 1.375 | 1.539 ± 0.515 | 46.777 ± 0.197 |