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Antiproliferative activity in TNBC cell lines (A) MDA-MB-231, (B) HCC1569, and (C) the normal breast epithelial cell line MCF12A with R-AST–OH (○), Rox(III) (▼), ATO (●), or reducing agent alone (△). (D) Permeability of arsenic compounds was measured using MDA-MB-231 cells. The significance of uptake is analyzed by one-way ANOVA test: *p < 0.05 (N = 3). Shown is the average, with SEM as error bars.
