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. 2024 May 28;24:393. doi: 10.1186/s12884-024-06589-7

Table 1.

Basic characteristics of the EFL and LPS groups

Characteristics EFL protocol(n = 1401) LPS protocol(n = 2129) Standardize diff. P-value
Maternal age (y) 30.17 ± 4.32 30.06 ± 4.51 0.02 (-0.04, 0.09) 0.47
Paternal age (y) 31.27 ± 5.38 31.21 ± 5.38 0.01 (-0.06, 0.08) 0.775
Maternal BMI (kg/m2) 22.48 ± 3.11 22.67 ± 3.15 0.06 (-0.00, 0.13) 0.068
Antral follicle count 13.69 ± 6.35 13.14 ± 5.83 0.09 (0.02, 0.16) 0.043
No. of oocytes retrieved 11.78 ± 5.05 11.32 ± 5.23 0.09 (0.02, 0.16) 0.01
Primary infertility 712 (50.97%) 1081 (51.01%) 0.00 (-0.07, 0.07) 0.978
Tubal factor 745 (53.18%) 1069 (50.21%) 0.06 (-0.01, 0.13) 0.085
PCOS 163 (11.63%) 160 (7.52%) 0.14 (0.07, 0.21) < 0.001
Male primary infertility 769 (55.44%) 1161 (54.89%) 0.01 (-0.06, 0.08) 0.749
Fertilization method 0.12 (0.05, 0.19) < 0.001
 IVF 1021 (72.88%) 1436 (67.45%)
 ICSI 380 (27.12%) 693 (32.55%)
No. of transferred embryos 1.90 ± 0.30 1.91 ± 0.42 0.01 (-0.06, 0.08) 0.793
Embryo transfer stage 0.09 (0.02, 0.16) 0.011
 Cleavage-stage embryo 1279 (91.29%) 1887 (88.63%)
 Blastocyst 122 (8.71%) 242 (11.37%)
Gestational age at delivery (wk) 38.52 ± 1.63 38.85 ± 1.68 0.19 (0.11, 0.28) < 0.001
Time of delivery (wk)
 <36 215 (15.74%) 255 (12.18%) 0.10 (0.03, 0.17) 0.003
 37–41 1119 (81.92%) 1793 (85.63%) 0.10 (0.03, 0.17) 0.004
 ≥ 42 0 (0.00%) 14 (0.67%) 0.12 (0.05, 0.18) 0.002
Delivery mode 0.05 (-0.01, 0.12) 0.117
 vaginal delivery 293 (21.45%) 405 (19.27%)
 cesarean delivery 1073 (78.55%) 1697 (80.73%)
Number of deliveries 0.05 (-0.02, 0.12) 0.127
 Singletons 995 (71.02%) 1562 (73.37%)
 Multiples 406 (28.98%) 567 (26.63%)
Congenital malformation 23 (1.64%) 50 (2.35%) 0.05 (-0.02, 0.12) 0.149
GDM 44 (3.14%) 19 (0.89%) 0.16 (0.09, 0.23) < 0.001

Note: Data are presented as mean ± SD for continuous variables or n (%) for categorical variables

BMI = body mass index; PCOS = polycystic ovary syndrome; ICSI = intracytoplasmic sperm injection; IVF = in vitro fertilization; GDM = gestational diabetes mellitus