Table 1.
Characteristics | EFL protocol(n = 1401) | LPS protocol(n = 2129) | Standardize diff. | P-value |
---|---|---|---|---|
Maternal age (y) | 30.17 ± 4.32 | 30.06 ± 4.51 | 0.02 (-0.04, 0.09) | 0.47 |
Paternal age (y) | 31.27 ± 5.38 | 31.21 ± 5.38 | 0.01 (-0.06, 0.08) | 0.775 |
Maternal BMI (kg/m2) | 22.48 ± 3.11 | 22.67 ± 3.15 | 0.06 (-0.00, 0.13) | 0.068 |
Antral follicle count | 13.69 ± 6.35 | 13.14 ± 5.83 | 0.09 (0.02, 0.16) | 0.043 |
No. of oocytes retrieved | 11.78 ± 5.05 | 11.32 ± 5.23 | 0.09 (0.02, 0.16) | 0.01 |
Primary infertility | 712 (50.97%) | 1081 (51.01%) | 0.00 (-0.07, 0.07) | 0.978 |
Tubal factor | 745 (53.18%) | 1069 (50.21%) | 0.06 (-0.01, 0.13) | 0.085 |
PCOS | 163 (11.63%) | 160 (7.52%) | 0.14 (0.07, 0.21) | < 0.001 |
Male primary infertility | 769 (55.44%) | 1161 (54.89%) | 0.01 (-0.06, 0.08) | 0.749 |
Fertilization method | 0.12 (0.05, 0.19) | < 0.001 | ||
IVF | 1021 (72.88%) | 1436 (67.45%) | ||
ICSI | 380 (27.12%) | 693 (32.55%) | ||
No. of transferred embryos | 1.90 ± 0.30 | 1.91 ± 0.42 | 0.01 (-0.06, 0.08) | 0.793 |
Embryo transfer stage | 0.09 (0.02, 0.16) | 0.011 | ||
Cleavage-stage embryo | 1279 (91.29%) | 1887 (88.63%) | ||
Blastocyst | 122 (8.71%) | 242 (11.37%) | ||
Gestational age at delivery (wk) | 38.52 ± 1.63 | 38.85 ± 1.68 | 0.19 (0.11, 0.28) | < 0.001 |
Time of delivery (wk) | ||||
<36 | 215 (15.74%) | 255 (12.18%) | 0.10 (0.03, 0.17) | 0.003 |
37–41 | 1119 (81.92%) | 1793 (85.63%) | 0.10 (0.03, 0.17) | 0.004 |
≥ 42 | 0 (0.00%) | 14 (0.67%) | 0.12 (0.05, 0.18) | 0.002 |
Delivery mode | 0.05 (-0.01, 0.12) | 0.117 | ||
vaginal delivery | 293 (21.45%) | 405 (19.27%) | ||
cesarean delivery | 1073 (78.55%) | 1697 (80.73%) | ||
Number of deliveries | 0.05 (-0.02, 0.12) | 0.127 | ||
Singletons | 995 (71.02%) | 1562 (73.37%) | ||
Multiples | 406 (28.98%) | 567 (26.63%) | ||
Congenital malformation | 23 (1.64%) | 50 (2.35%) | 0.05 (-0.02, 0.12) | 0.149 |
GDM | 44 (3.14%) | 19 (0.89%) | 0.16 (0.09, 0.23) | < 0.001 |
Note: Data are presented as mean ± SD for continuous variables or n (%) for categorical variables
BMI = body mass index; PCOS = polycystic ovary syndrome; ICSI = intracytoplasmic sperm injection; IVF = in vitro fertilization; GDM = gestational diabetes mellitus