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. 2024 Apr 1;14(2):e2024099. doi: 10.5826/dpc.1402a99

Table 1.

Sociodemographic characteristics and disease-related features of the patients.

Characteristics Mean ± SD or N (%)

Age, χ̄ ± s.s. (median) (year) 50,06 ± 14.88 (52.00)

Gender
Female 51 (48.11)
Male 55 (51.89)

Body mass index (χ̄ ± s.s. (median) 26.88 ± 4.04 (26.77)

Comorbidities
Hypertension 17 (16.04)
Diabetes 19 (17.92)
Dyslipidemia 4 (3.77)
Thyroid dysfunction 6 (5.66)
Coronary artery disease 12 (11.32)
Liver diseases 2 (1.89)
Others (neurological, rheumatological, chronic obstructive pulmonary diseases) 6 (5.66)

Duration of disease (months) 7.59 ± 8.57 (4.00)

Delay in diagnosis (months) 4.39 ± 5.26 (3.00)

Age-onset of pemphigus χ̄ ± s.s. (median) 49.45 ± 14.98 (51.00)

Family history of pemphigus 1 (0.94)

Retained body surface area
Localized 57 (53.77)
Generalized 49 (46.23)

Clinical subtype
Mucocutaneous 83 (78.30)
Mucosal 23 (21.70)

Onset location
Oral mucosa 44 (41.51)
Skin 8 (7.55)
Oral mucosa and skin (both) 43 (40.57)
Scalp 1 (0.94)
Nasal mucosa 2 (1.89)
Oral mucosa & skin & scalp 2 (1.89)
Oral nasal anogenital 5 (4.72)
Oral nasal skin 1 (0.94)

Involvement site in the oral mucosa
Bilateral buccal mucosa 67 (63.21)
Hard palate 50 (47.17)
Lower lip 49 (46.23)
Tongue 48 (45.28)
Gingiva 43 (40.57)
Soft palate 40 (37.74)
Upper lip 33 (31.13)
Floor of mouth 29 (27.36)
Oropharynx 22 (20.75)
Unilateral buccal mucosa 18 (16.98)

Symptom in the oral mucosa 104 (98.11)
Burning 91 (85.85)
Pain 82 (77.36)
Dysphagia 1 (0.94)

Clinical findings in the oral mucosa
Erosions 91 (85.85)
Superficial ulcer 70 (66.04)
Small vesicles 13 (12.26)
Flaccid bullae 11 (10.38)

Diameter of the lesion in the oral mucosa
< 1 cm 45 (42.45)
≥ 1 cm 61 (57.55)

PDAI, χ̄ ± s.s. (median) 27.58 ± 21.28 (20.50)

Damage score 0.89 ± 3.01

PDAI = Pemphigus disease area index.