Table 1.
Characteristics | Mean ± SD or N (%) |
---|---|
| |
Age, χ̄ ± s.s. (median) (year) | 50,06 ± 14.88 (52.00) |
| |
Gender | |
Female | 51 (48.11) |
Male | 55 (51.89) |
| |
Body mass index (χ̄ ± s.s. (median) | 26.88 ± 4.04 (26.77) |
| |
Comorbidities | |
Hypertension | 17 (16.04) |
Diabetes | 19 (17.92) |
Dyslipidemia | 4 (3.77) |
Thyroid dysfunction | 6 (5.66) |
Coronary artery disease | 12 (11.32) |
Liver diseases | 2 (1.89) |
Others (neurological, rheumatological, chronic obstructive pulmonary diseases) | 6 (5.66) |
| |
Duration of disease (months) | 7.59 ± 8.57 (4.00) |
| |
Delay in diagnosis (months) | 4.39 ± 5.26 (3.00) |
| |
Age-onset of pemphigus χ̄ ± s.s. (median) | 49.45 ± 14.98 (51.00) |
| |
Family history of pemphigus | 1 (0.94) |
| |
Retained body surface area | |
Localized | 57 (53.77) |
Generalized | 49 (46.23) |
| |
Clinical subtype | |
Mucocutaneous | 83 (78.30) |
Mucosal | 23 (21.70) |
| |
Onset location | |
Oral mucosa | 44 (41.51) |
Skin | 8 (7.55) |
Oral mucosa and skin (both) | 43 (40.57) |
Scalp | 1 (0.94) |
Nasal mucosa | 2 (1.89) |
Oral mucosa & skin & scalp | 2 (1.89) |
Oral nasal anogenital | 5 (4.72) |
Oral nasal skin | 1 (0.94) |
| |
Involvement site in the oral mucosa | |
Bilateral buccal mucosa | 67 (63.21) |
Hard palate | 50 (47.17) |
Lower lip | 49 (46.23) |
Tongue | 48 (45.28) |
Gingiva | 43 (40.57) |
Soft palate | 40 (37.74) |
Upper lip | 33 (31.13) |
Floor of mouth | 29 (27.36) |
Oropharynx | 22 (20.75) |
Unilateral buccal mucosa | 18 (16.98) |
| |
Symptom in the oral mucosa | 104 (98.11) |
Burning | 91 (85.85) |
Pain | 82 (77.36) |
Dysphagia | 1 (0.94) |
| |
Clinical findings in the oral mucosa | |
Erosions | 91 (85.85) |
Superficial ulcer | 70 (66.04) |
Small vesicles | 13 (12.26) |
Flaccid bullae | 11 (10.38) |
| |
Diameter of the lesion in the oral mucosa | |
< 1 cm | 45 (42.45) |
≥ 1 cm | 61 (57.55) |
| |
PDAI, χ̄ ± s.s. (median) | 27.58 ± 21.28 (20.50) |
| |
Damage score | 0.89 ± 3.01 |
PDAI = Pemphigus disease area index.