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. 2024 May 29;84(5):443–458. doi: 10.1055/a-2286-6066

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ )

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 6 — Progression-free survival in the BioItaLEE trial depending on the changes in serum thymidine kinase activity under therapy with ribociclib 15 . HR = hazard ratio, mPFS = median progression-free survival, sTKa = serum thymidine kinase activity

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