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. 1998 Aug 8;317(7155):405–409. doi: 10.1136/bmj.317.7155.405

Table 1.

Probabilities of various events occurring after suspected myocardial infarction according to treatment received by a typical patient in the trials and according to whether myocardial infarction has occurred. Probabilities are expressed as percentages

Probability of outcome Treatment
Aspirin Streptokinase Tissue plasminogen activator
Given myocardial infarction:
 Dying of myocardial infarction 11.5 11.5×0.75=8.6* 8.6×0.8=6.9*
 Surviving cerebrovascular accident  0.2 0.5 0.7
 Dying of cerebrovascular accident  0.2 0.5 0.7
 Dying of haemorrhage or anaphylaxis 0 0.2  0.18
 Surviving without stroke 88.1 90.2   91.5
Given no myocardial infarction:
 Dying of another cause  2.0 2.0 2.0
 Surviving stroke 0 0.4 0.6
 Dying of stroke 0 0.4 0.6
 Dying of complications 0 0.08   0.06
 Surviving without impairment 98 97.1   96.7
*

Streptokinase reduces the risk of dying by 25 percentage points when compared with aspirin alone; tissue plasminogen activator may reduce the risk of dying by a further 20 percentage points.7 

Calculated as 100 minus the sum of the four probabilities above.