Table 1.
Probability of outcome | Treatment
|
||
---|---|---|---|
Aspirin | Streptokinase | Tissue plasminogen activator | |
Given myocardial infarction: | |||
Dying of myocardial infarction | 11.5 | 11.5×0.75=8.6* | 8.6×0.8=6.9* |
Surviving cerebrovascular accident | 0.2 | 0.5 | 0.7 |
Dying of cerebrovascular accident | 0.2 | 0.5 | 0.7 |
Dying of haemorrhage or anaphylaxis | 0 | 0.2 | 0.18 |
Surviving without stroke† | 88.1 | 90.2 | 91.5 |
Given no myocardial infarction: | |||
Dying of another cause | 2.0 | 2.0 | 2.0 |
Surviving stroke | 0 | 0.4 | 0.6 |
Dying of stroke | 0 | 0.4 | 0.6 |
Dying of complications | 0 | 0.08 | 0.06 |
Surviving without impairment† | 98 | 97.1 | 96.7 |
Streptokinase reduces the risk of dying by 25 percentage points when compared with aspirin alone; tissue plasminogen activator may reduce the risk of dying by a further 20 percentage points.7
Calculated as 100 minus the sum of the four probabilities above.