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Potential therapeutic drug targets against SARS-CoV-2
| SARS-CoV-2 | Host |
|---|---|
| Spike protein | Proteases of host |
| Envelope protein | Proprotein convertase (PPC) |
| Membrane protein | Toll-like receptors (TLRs) |
| Nucleoprotein | High-density lipoprotein (HDL) scavenger receptor B type 1 (SR-B1) |
| Replicase protein | Glycosaminoglycans (GAGs) on the cell surface |
| Main protease (Mpro or 3CLpro) | |
| Papine-like protease | |
| RNA-dependent RNA polymerase | |
| Non-structural proteins |
