Fig. 1.

Upregulation of several tissue-homing genes on plasma cells and plasmablasts during the acute phase in DENV-infected patients.

(A). Uniform Manifold Approximation and Projection (UMAP) plot showing integrated B cell subsets from the DENV-infected patients and healthy controls as colored by cell types.

(B). Relative abundances of B cell subsets during acute, late convalescent phases (two weeks after defervescence), and healthy controls.

(C). Dot plot representing the average expression values of tissue-homing genes in each B cell subset during the acute and late convalescent phases. Color intensity represents the relative expression levels and dot size represents the fraction of cells within cell type expressing a given gene.

PCs = plasma cells, PBs = plasmablasts, DF = dengue fever, DHF = dengue hemorrhagic fever, HC = healthy control, and Late con = late convalescent phase. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)