Table 1.
Characteristics of included patients with severe yellow fever infection.
| Characteristics | All patients (N = 35) |
|---|---|
| Length of stay in hospital (d), median (IQR) | 10 (7-17) |
| Socio-demographic characteristics | |
| Age (y), median (IQR) | 49 (39-55) |
| Male sex, n (%) | 33 (94) |
| Skin color, n (%) | |
| Mixed | 17 (48.6) |
| White | 11 (31.4) |
| Black | 7 (20) |
| Clinical characteristics | |
| Weight (kg), median (IQR) | 70 (56-85) |
| BMIa (kg/m2), median (IQR) | 25 (22.2-30.4) |
| Heart rate (beats/min), median (IQR) | 81 (69-98) |
| Respiratory rate (breaths/min), median (IQR) | 20 (18-23) |
| Median MABP (IQR) | 94 (75-99) |
| Temperature (°C), median (IQR) | 36 (36.0-37.0) |
| Alcoholisma, n (%) | 17 (48.5) |
| Smokinga, n (%) | 13 (37.1) |
| Vaccination for YF, n (%) | 8 (23) |
| Bleedinga, n (%) | 21 (60) |
| Major bleedinga, n (%) | 14 (66) |
| Hepatic encephalopathy, n (%) | 19 (58) |
| Other infectionb, n (%) | 13 (39) |
| Median No. of SIRS (IQR) | 1.0 (1.0-2.5) |
| Kidney failure, n (%) | 15 (46) |
| Death, n (%) | 12 (34) |
| Laboratory tests | |
| Total bilirubina (mg/dL), median (IQR) | 5.7 (4.0-13.5) |
| AST (units/L), median (IQR) | 4350 (1171-7723) |
| Median INR (IQR) | 1.4 (1.0-1.8) |
| Creatinine at admission (mg/dL), median (IQR) | 1.0 (0.7-2.6) |
| Total leukocytes (μL), median (IQR) | 5400 (3500-8850) |
| Blood transfusion | |
| Fresh frozen plasmaa, n (%) | 19 (68) |
| Cryoprecipitatea, n (%) | 17 (61) |
| Packed red cellsa, n (%) | 15 (54) |
| Plateletsa, n (%) | 17 (61) |
AST, aspartate aminotransferase; BMI, body mass index; INR, international normalized ratio; MABP, mean arterial blood pressure; SIRS, systemic inflammatory response syndrome; YF, yellow fever.
a
There are some missing data for these variables.
b
All patients had a bacterial infection.