Table 1. Systems Simulated Specifically for This Work^a.

lipid:salt	force field	ion (M)	Nl	Nw	Nc	T (K)	ts (ns)	ta (ns)	teq	files [ref]
POPC	Drude2017	0	144	6400	0	303	500	400	5.79	(81)
	Drude2023	0	72	2239	0	303	300	200	2.29 ± 0.13	(82, 60)
POPE	Drude2017	0	144	6400	0	308	350	300	5.79	(83)
	Drude2023	0	72	2304	0	303	300	200	1.71 ± 0.10	(59, 84)
	AMOEBA	0	72	2880	0	303	306	306	0.43	(85)
POPC:NaCl	Drude2017	0.350	144	6400	41	303	500	400	3.31	(86)
	Drude2017	0.450	144	6400	51	303	500	400	2.5	(87)
	Drude2017	0.650	144	6400	77	303	500	400	3.30	(88)
	Drude2017	1.0	144	6400	115	303	500	400	4.06	(89)
	Drude2023	0.350	128	6400	41	303	224	220	2.63	(90)
	Drude2023	1.0	128	6400	115	303	220	220	2.77	(91)
POPC:CaCl2	Drude2017	0.350	144	6400	41	303	500	400	2.45	(92)
	Drude2017	0.450	144	6400	52	303	500	400	2.56	(93)
	Drude2017	0.650	144	6400	76	303	500	400	4.46	(94)
	Drude2017	1.0	144	6400	114	303	500	400	5.00	(95)
	Drude2023	0.350	128	6400	41	303	219	219	2.63	(96)
	Drude2023	0.790	128	6400	91	303	214	214	4.32	(97)
DOPC	AMOEBA	0	72	2880	0	303	202	202	0.62	(98)
DOPC:NaCl	AMOEBA	0.450	72	2880	17	303	218	218	0.60	(99)
	AMOEBA	1.0	72	2880	35	303	202	202	0.61	(100)
DOPC:CaCl2	AMOEBA	0.450	72	2880	16	303	218	218	0.53	(101)
	AMOEBA	1.0	72	2880	36	303	218	218	0.66	(102)

^aColumn N_l gives the number of lipids, N_w the number of water molecules, and T (K) denotes the temperature in kelvins. The salt concentrations in column “ion (M)” is calculated from the number of cations N_c as [salt] = N_c × [water]/N_w, where [water] = 55.5 M. Simulated time is listed in column t_s and time used for analysis in t_a. Column t_eq gives the relative equilibration times with respect to the trajectory lengths based on PCAlipids^76,77 and computed using the NMRlipids Databank:⁴⁰t_eq < 1 indicates convergence, t_eq > 1 indicates the presence of a longer time-scale than the trajectory length. Column “files [ref]” gives the reference to openly accessible simulation data.