Table 3. Meta-Regression Models Testing the Covariates Carbon Chain Length and PFAS Class (Tertile 2 or 3 Versus 1) with Different Cortisol Pools. Meta-regression findings are presented as the ratio of the measures of association [i.e., the quantile ratio of cortisol (free, bound, or total) for greater than 1st tertile vs. 1st tertile (i.e., pooling 2nd and 3rd tertile effects)], among one level of the tested covariate vs. the other level of the tested covariate.
Associations of covariates with the
estimated PFAS-cortisol pool
associations | ||||
---|---|---|---|---|
covariate | cortisol pool | quantile ratio ratio | lower 95% CI | upper 95% CI |
carbon chain length (≥ 10 versus < 10 carbons) | free | 0.88 | 0.78 | 0.97 |
bound | 1.08 | 1.03 | 1.13 | |
total | 0.95 | 0.89 | 1.02 | |
PFAS class (PFSA versus PFCA) | free | 0.83 | 0.70 | 0.97 |
bound | 1.11 | 1.01 | 1.21 | |
total | 0.94 | 0.83 | 1.05 |