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. 2024 May 14;58(21):9061–9070. doi: 10.1021/acs.est.3c06979

Table 3. Meta-Regression Models Testing the Covariates Carbon Chain Length and PFAS Class (Tertile 2 or 3 Versus 1) with Different Cortisol Pools. Meta-regression findings are presented as the ratio of the measures of association [i.e., the quantile ratio of cortisol (free, bound, or total) for greater than 1st tertile vs. 1st tertile (i.e., pooling 2nd and 3rd tertile effects)], among one level of the tested covariate vs. the other level of the tested covariate.

Associations of covariates with the estimated PFAS-cortisol pool associations
covariate cortisol pool quantile ratio ratio lower 95% CI upper 95% CI
carbon chain length (≥ 10 versus < 10 carbons) free 0.88 0.78 0.97
  bound 1.08 1.03 1.13
  total 0.95 0.89 1.02
PFAS class (PFSA versus PFCA) free 0.83 0.70 0.97
  bound 1.11 1.01 1.21
  total 0.94 0.83 1.05