Table 3. Adjusted Association between PM1, PM2.5, PM1–2.5, and Maternal Thyroid Autoimmunity with TPOAb Positivity in the First Trimester.
crude
model |
adjusted modela |
|||
---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | |
PM1 | 1.06 (0.98, 1.14) | 0.151 | 1.05 (0.97, 1.13) | 0.198 |
PM1–2.5 | 1.14 (1.08, 1.21) | <0.001 | 1.15 (1.08, 1.22) | <0.001 |
PM2.5 | 1.06 (1.01, 1.12) | 0.017 | 1.06 (1.01, 1.12) | 0.024 |
Adjusted for the maternal age, prepregnancy BMI, annual household income, ethnicity, educational levels, smoking status, drinking status, gravidity, seasons of enrollment, and gestational weeks. PM1, particulate matter with an aerodynamic diameter less than or equal to 1 μm; PM1–2.5, particulate matter with an aerodynamic diameter between 1 and 2.5 μm; PM2.5, particulate matter with an aerodynamic diameter less than or equal to 2.5 μm; TPOAb, thyroid peroxidase antibodies; OR, odds ratio; and 95% CIs, confidence intervals.