Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 May 30;22:517. doi: 10.1186/s12967-024-05233-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 3 — CircDCAF8 promoted HCC proliferation and metastasis in vivo. A Tumors formed in nude mice by subcutaneous injection of circDCAF8 stable knockdown or overexpression cells. B, C The volume and weight of the subcutaneous tumor. D H&E, Ki67, E-cadherin, N-cadherin and Vimentin staining of xenograft tumors. Scale bar = 50 μm. E Fluorescence intensity alterations in pulmonary metastasis models. F Lung metastasis induced by tail vein injection of circDCAF8 knockdown or overexpression cells in nude mice. G Lung metastatic nodules were counted. H H&E stain of lung metastases. Scale bar = 200 μm. n = 6 mice per group. Data are presented as means ± SDs. (*p < 0.05; **p < 0.01; ***p < 0.001)