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. 2024 May 30;22:520. doi: 10.1186/s12967-024-05347-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 11 — Biomimetic nanoparticles encapsulating DTX for lung cancer treatment. A Schematic representation of in vivo delivery using PM/PLGA/DTX nanoparticles. B Graph showing the release of DTX in vitro in PBS (pH 7.4) at 37 °C for PLGA/DTX, PM/PLGA/DTX, and free DTX, with averages shown as mean ± SD (n = 3). C The volume of tumors in mice and D the rates of tumor suppression following administration of free DTX, PLGA/DTX, and PM/PLGA/DTX, reported as mean ± SD (n = 8), ***P < 0.001. E Examination of tissue pathology; H&E-stained tumor tissue images from treatments with free DTX, PLGA/DTX, and PM/PLGA/DTX. Scale bar = 50 μm. F Quantitative assessment of the necrotic areas within tumors for each treatment group

(Reprinted with permission from [105])