Fig. 3.
Depiction of RGD_PLGA Nanoparticles with DTX. A Schematic of PLGA-NPs. B In vivo effect of PLGA-NP on tumor diameter at the end of the experiment. *p < 0.05; **p < 0.01; two-way ANOVA. A study of the MRI and histological characteristics of 4T1 tumors obtained from mice. C Representative axial T2w-MR images of tumor region in mice with RGD_PLGA, Ctrl_ PLGA, free DTX, or physiological saline solution as a control (N = 6 per group). D Representative tumors from four treatment groups were histologically stained with hematoxylin/eosin. Necrotic areas are indicated by red arrows
(Reprinted with permission from [77])