Table 4.
Multivariable analysis of locoregional control (LRC) and overall survival (OS) based on proposed lymph node assessment method
| Variable | LRC | OS | ||
|---|---|---|---|---|
| p | HR [95%CI] | p | HR [95%CI] | |
| Age (> 65/≤65) | 0.047 | 2.90 [1.01–8.30] | ||
| Immunosuppression | 0.014 | 2.49 [1.86–8.28] | 0.022 | 3.60 [1.20−10.82] |
| Tumor stage (T3−4 vs. T1−2) | 0.006 | 2.30 [1.97–5.46] | 0.017 | 3.96 [1.79–8.86] |
| Positive margin | < 0.001 | 29.39 [7.67–112.60] | < 0.001 | 22.50 [5.79–87.46] |
| Proposed stage | ||||
| N1 | ||||
| N2 | 0.011 | 6.80 [1.55–29.95] | 0.020 | 6.43 [1.35–30.67] |
| N3 | < 0.001 | 20.12 [5.16–78.50] | < 0.001 | 13.89 [3.26–59.09] |
| Radiotherapy | 0.099 | 0.89 [0.77–1.18] | 0.087 | 0.94 [0.86–1.32] |