Table 3.
Results of MR‒Egger pleiotropy test and heterogeneity test of univariate Mendelian randomization analysis
Outcome | Exposure | Pleiotropy test | Heterogeneity test | |
---|---|---|---|---|
P-value | MR Egger | IVW | ||
KOA | ALM | 0.981 | 2.15 × 10–55 | 3.30 × 10–55 |
LHG | 0.448 | 0.226 | 0.233 | |
UWP | 0.698 | 0.228 | 0.280 | |
HOA | ALM | 0.442 | 5.84 × 10–42 | 6.11 × 10–42 |
LHG | 0.186 | 9.66 × 10–6 | 3.58 × 10–7 | |
UWP | 0.228 | 0.247 | 0.208 |
KOA Knee osteoarthritis, HOA Hip osteoarthritis, ALM Appendicular lean mass, LHG Low hand grip, UWP Usual walking pace, IVW Inverse variance weighting