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. 2024 May 29;24:469. doi: 10.1186/s12877-024-05098-8

Table 3.

Results of MR‒Egger pleiotropy test and heterogeneity test of univariate Mendelian randomization analysis

Outcome Exposure Pleiotropy test Heterogeneity test
P-value MR Egger IVW
KOA ALM 0.981 2.15 × 10–55 3.30 × 10–55
LHG 0.448 0.226 0.233
UWP 0.698 0.228 0.280
HOA ALM 0.442 5.84 × 10–42 6.11 × 10–42
LHG 0.186 9.66 × 10–6 3.58 × 10–7
UWP 0.228 0.247 0.208

KOA Knee osteoarthritis, HOA Hip osteoarthritis, ALM Appendicular lean mass, LHG Low hand grip, UWP Usual walking pace, IVW Inverse variance weighting