Table 2.

Pregnancy outcome for pSS cases and control individuals

	pSS (n=164)	Controls (n=328)	Adjusted OR	95% CI	P value
Fetal loss*	36 (21.95%)	12 (3.66%)
Spontaneous miscarriage	21 (12.80%)	5 (1.52%)	11.335	(4.128 to 31.123)	<0.001
Duration of spontaneous miscarriage (day)†	69.50±42.33	155.43±30.48
Therapeutic miscarriage	10 (6.10%)	3 (0.91%)	10.268	(2.646 to 39.846)	0.001
Other‡	5 (3.05%)	4 (1.22%)	2.319	(0.572 to 9.412)	0.239
Oligohydramnios*	26 (15.85%)	35 (10.67%)	1.672	(0.936 to 2.989)	0.083
Eclampsia/pre-eclampsia*	2 (1.22%)	5 (1.52%)	0.319	(0.042 to 2.430)	0.270
Threatened preterm birth*	7 (4.27%)	3 (0.91%)	3.896	(0.925 to 16.412)	0.064
Premature rupture of membranes*	23 (14.02%)	56 (17.07%)
Premature rupture of membranes in preterm	16 (9.76%)	50 (15.24%)	0.728	(0.391 to 1.356)	0.317
Premature rupture of membranes in full term	7 (4.27%)	6 (1.83%)	1.671	(0.502 to 5.564)	0.403
Placental abnormalities on ultrasound*	24 (14.63%)	21 (6.40%)	2.295	(1.182 to 4.457)	0.014
Placenta previa	6 (3.66%)	6 (1.83%)
Placental abruption	1 (0.61%)	3 (0.91%)
Hydatid mole	1 (0.61%)	0 (0%)
Placenta implantation	3 (1.83%)	1 (0.30%)
Placental adherence	9 (5.49%)	4 (1.22%)
Placental thrombosis	1 (0.61%)	0 (0%)
placental fibrin deposition	6 (3.66%)	0 (0%)
Placental infarction	1 (0.61%)	0 (0%)
Placental haematoma or bleeding	5 (3.05%)	5 (1.52%)
Chorioamnionitis	4 (2.44%)	1 (0.30%)
Veil-shaped placenta	2 (1.22%)	3 (0.91%)
Racquet-shaped placenta	2 (1.22%)	1 (0.30%)
Pregnancy-induced hypertension*	6 (3.66%)	6 (1.83%)	2.367	(0.624 to 8.978)	0.205
Gestational diabetes mellitus*	18 (10.98%)	27 (8.23%)	1.339	(0.673 to 2.666)	0.406

Data were analysed by generalised linear regression method logistic.

*Number with the percentages between brackets.

†Mean±SD.

‡Including stillbirth, ectopic pregnancy, hydatidiform mole.

n, number of deliveries; pSS, primary Sjögren’s syndrome.