Time-scaled phylogenetic tree of 43 highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b complete viral genomes from seals and wild birds in the St. Lawrence Estuary, Quebec, Canada, 2022. Tree was inferred by Bayesian analysis. Red text indicates seal-derived sequences and black text indicates wild bird–derived sequences. Posterior probability values >0.70 are displayed at the tree nodes. The genome constellation for each sequence (i.e., the compliment of Eurasian and North American derived genome segments) is presented to the right of the tree tips. HA, hemagglutinin; M, matrix; NA, neuraminidase; NP, nucleoprotein; NS, nonstructural; PA, polymerase acidic; PB, polymerase basic.