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. 2024 Jun;30(6):1285–1288. doi: 10.3201/eid3006.240192

Table. Nucleotide sequence identities between gene segments of novel clade 2.3.4.4b highly pathogenic avian influenza A(H5N6) virus isolate A/whooper swan/Korea/23WC075/2023 from South Korea and nearest top 3 homologs in the GISAID EpiFlu database*.

Gene Top 3 query Accession no. Nucleotide identity % Identity
PB2
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 1 (PB2) EPI2898974 2280/2280 100.00
A/environment/chongqing/1795/2023 (A/H9N2) segment 1 (PB2) EPI2841012 2271/2280 99.61
A/environment/Kagoshima/KU-I6/2021 (H4N6) (A/H4N6) segment 1 (PB2)
 EPI2553141
 2253/2280
 98.82
PB1
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 2 (PB1) EPI2898975 2273/2274 99.96
A/egret/Korea/22WC394/2023 (A/H5N1) segment 2 (PB1) EPI2743089 2271/2274 99.87
A/common buzzard/Korea/22WC336/2023 (A/H5N1) segment 2 (PB1)
 EPI2742993
 2271/2274
 99.87
PA
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 3 (PA) EPI2898976 2150/2151 99.95
A/common teal/Amur region/92b/2020 (A/H6N2) segment 3 (PA) EPI1849993 2142/2151 99.58
A/mallard/Russia Primorje/94T/2020 (A/H1N1) segment 3 (PA)
 EPI1849961
 2141/2151
 99.54
HA
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 4 (HA) EPI2898977 1700/1704 99.77
A/environment/Kagoshima/KU-G4/2022 (H5N1) (A/H5N1) segment 4 (HA) EPI2789597 1697/1704 99.59
A/environment/Kagoshima/KU-D4/2022 (H5N1) (A/H5N1) segment 4 (HA)
 EPI2789589
 1697/1704
 99.59
NP
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 5 (NP) EPI2898978 1496/1497 99.93
A/gadwall/Novosibirsk region/3407k/2020 (A/H4N6) segment 5 (NP) EPI1849870 1479/1497 98.80
A/mallard/Novosibirsk region/3286k/2020 (A/H4N6) segment 5 (NP)
 EPI1849878
 1478/1497
 98.73
NA
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 6 (NA) EPI2898979 1377/1380 99.78
A/duck/Hunan/S40199/2021(H5N6) (A/H5N6) segment 6 (NA) EPI1997201 1360/1380 98.55
A/Changsha/1/2022 (A/H5N6) segment 6 (NA)
 EPI2287050
 1359/1380
 98.48
M
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 7 (MP) EPI2898980 982/982 100.00
A/northern pintail/Kagoshima/KU-64/2022 (H5N1) (A/H5N1) segment 7 (MP) EPI2794001 980/982 99.80
A/environment/Kagoshima/KU-B4/2022 (H5N1) (A/H5N1) segment 7 (MP)
 EPI2789385
 980/982
 99.80
NS
 A/peregrine falcon/Saga/4112A002/2023 (A/H5N6) segment 8 (NS) EPI2898981 837/838 99.88
A/bean goose/Korea/KNU-10/2022 (A/H10N7) segment 8 (NS) EPI2873490 836/838 99.76
A/bean goose/Korea/KNU-14/2022 (A/H6N1) segment 8 (NS)
 EPI2873460
 836/838
 99.76
*GISAID, https://www.gisaid.org; HA, hemagglutinin; P, matrix; NA, neuraminidase; NP, nucleoprotein; NS, nonstructural; PA, polymerase acidic; PB, polymerase basic.