Table 3.
Comparison of 185 IVF patients with and without inferolateral MAD
| IVF patients with inferolateral MAD (n = 24) | IVF patients without inferolateral MAD (n = 161) | P-value | |
|---|---|---|---|
| Age, yearsa | 29 (22, 49)] | 39 (28, 53) | 0.140 |
| Female, n (%) | 10 (42%) | 64 (40%) | 0.858 |
| History of syncope, n (%) | 3/18 (17%) | 16/149 (11%) | 0.436 |
| History of palpitations, n (%) | 3/18 (17%) | 18/149 (12%) | 0.704 |
| Family history of SCDb, n (%) | 2/20 (10%) | 20/150 (13%) | 1.000 |
| Arrhythmia characteristics | |||
| Inverted/biphasic T-waves inferior, n (%) | 9 (38%) | 25/159 (16%) | 0.021 |
| High PVC burden, n (%) | 16 (67%) | 36 (23%) | <0.001 |
| Multi-form PVCs | 9/15 (60%) | 12/31 (39%) | 0.174 |
| Non-sustained VT, n (%) | 15 (63%) | 62/152 (41%) | 0.046 |
| Appropriate ICD therapy, n (%) | 3 (13%) | 29 (18%) | 0.579 |
| Death, n (%) | 0 (0%) | 3 (2%) | 1.000 |
| CMR characteristics | |||
| LVEF, %c | 55 (±7) | 58 (±8) | 0.108 |
| Mitral valve prolapse, n (%) | 10 (42%) | 3 (2%) | <0.001 |
| MAD present in multiple areas, n (%) | 20 (83%) | 33 (21%) | <0.001 |
| LGE present, n (%) | 2/23 (9%) | 11/145 (8%) | 0.693 |
CMR, cardiac magnetic resonance; IVF, idiopathic ventricular fibrillation; ICD, implantable cardioverter defibrillation; LGE, late gadolinium enhancement; LVEF, left ventricular ejection fraction; MAD, mitral annular disjunction; SCD, sudden cardiac death; PVC, premature ventricular complexes; VT, ventricular tachycardia.
aValues are presented as median (interquartile range).
bDefinition as used in Table 1.
cValues are presented as mean (standard deviation).