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. Author manuscript; available in PMC: 2025 Jun 1.
Published in final edited form as: Am J Obstet Gynecol. 2023 Dec 17;230(6):583–599.e16. doi: 10.1016/j.ajog.2023.12.014

TABLE 4.

Occupational lifting and employment outcomes during pregnancy

Author, Year Design Overall Exposure Assessment Lifting Exposure Effect measure Effect Size Outcome

Utility Freq Timing Reference Categories (95% CI)

Pedersen, 202123 Prospective cohort +++ 2 12 and 27 GW No heavy lifting Heavy lifting any GW
Heavy lifting at 12 GW but not 27 GW
Heavy lifting at 27 GW but not 12 GW
Heavy lifting at 12 and 27 GW
Adj OR 2.10 (1.30, 3.50)
0.80 (0.20, 2.80)

3.70 (1.80, 7.60)

3.20 (1.80, 5.40)
Sick leave ≥14 days ≤27 GW (0, 1)

Guendelman, 201634 Case-control ++ 1 Retrospective (4.5 months postpartum), for each trimester No lift >6.8 kg and no standing ≥4 hours Lift >6.8 kg in trimesters 1 & 2 Adj OR 4.20 (1.98, 8.90) Employment withdrawal during pregnancy (0, 1)

Hansen, 201525 Prospective cohort ++ 1 17 GW (median) ≤10 kg
≤20 kg


0–14 kg
Lifting 11–20 kg
Lifting >20 kg
Cumulative lifting:
15–100 kg
101–200 kg
201–500 kg
501–1000 kg
>1000 kg
Trend
Adj HR 1.77 (1.70, 1.84)
1.83 (1.74, 1.92)

1.58 (1.49, 1.67)
2.01 (1.87, 2.17)
2.18 (2.02, 2.35)
2.26 (1.99, 2.56)
3.02 (2.54, 3.58)
1.29 (1.27–1.31)a
First sick leave onset lasting >15 days occurring 10–29 GW (0, 1)b

Kaerlev, 200432 Retrospective cohort + 1 Retrospective (after delivery) No heavy lifting Heavy lifting NOS Adj OR 1.90 (1.30, 2.90) Length of antenatal leave >10% of work time (0, 1)

Strand, 199733 Retrospective cohort + 1 Retrospective (at delivery) for when pregnancy confirmed Lift <10 kg Heavy lifting 10–20 kg Adj OR
Adj OR
1.26 (1.01, 1.57)c
1.48 (1.22, 1.80)
Antenatal leave >8 weeks before delivery (0, 1) >3 weeks before delivery (0, 1)

Adj, adjusted; CI, confidence interval; HR, Freq, frequency; hazard ratio; kg, kilograms; NOS, not otherwise specified; OR, odds ratio; RR, relative risk; (0, 1), binary outcome (no, yes).

a

For self-reported cumulative total lifting per day, a positive exposure-response relationship was observed

b

The source publication reports time-dependent effects of the exposures measured by time-varying coefficients (Table 4).25

c

The source publication reports a lower confidence interval of 0.01 for ‘lifting heavy loads (10–20 kg)’ believed to be an error based on the comparable sample size and effect estimate for exposure to ‘standing back bent forward’ (Table 3).34